Liquid chromatography systems pump solvents or buffers through the system to separate compounds of Interest. It is critically important that only liquids are pumped without air bubble formation. Air bubble formation creates problems with the column, the flow cell for the detector and also causes noisy baselines. It is essential that the dissolved gasses in the solvent or buffer system be removed to ensure the precision, accuracy and performance of the liquid chromatography system. The pump is unable to discern between a solvent or buffer that has or is devoid of gasses. Online degassing removes the dissolved gasses from the liquid flow preventing bubble formation, ensuring column stability and eliminating bubbles in the flow cell. This reduces the Baseline noise and improves Baseline stability.
All liquid chromatography including uHPLC, HPLC, FPLC, ion chromatography and LC mass spec benefit from on-line degassing
Other online degassers that are available in the marketplace use a tubular membrane in a cassette. A vacuum pump pulls the gas out of the liquid through the tubing to accomplish continuous gas removal. This has been the de facto standard for many years. Several years back, standard Teflon tubing was replaced with Teflon AF tubing. This improved both the permeability and the efficiency of the degassing process.
Icon Scientific, Inc. introduces a line of the highest efficiency online hplc degassers in the marketplace. These can be used for uHPLC, HPLC, FPLC, ion chromatography and hplc mass spec. Our degassers use a patented planner degassing chamber. This state-of-the-art technology utilizes an entirely different internal structure while maintaining a very small size. This arrangement has single flow plate sandwiched between two vacuum plates coated with Teflon AF thin films. This dual film plannar degasser technology is so unique it is patented. Tubular degassing Chambers are intrinsically less efficient. Some additional advantages of our degassing chamber is our Superior bubble removal and faster pull down times. We have the highest efficiency with the lowest pressure drops enabling our system to have the lowest internal volumes in the industry. Our systems can be used with reverse phase and normal phase HPLC solvents as well as a buffer systems used in FPLC, because only PEEK and Teflon AF are used in the flow path.
All other brands of degassers contain internal fittings. Icon Scientifics online dual film planar degasser has no internal fittings or connections in the degasser chamber. Internal fittings have been eliminated on our design to avoid any risk of internal leakage. Dual film planar degasser modules offer the highest efficiency degassing with the lowest pressure drop across the system. This enables our systems to have the lowest internal volumes available in the marketplace. Icon’s dual film planar degasser technology is available in two different size cartridges depending on the flow rate desired.
Icon Scientific offers Superior technology and performance at a similar price point compared to ordinary degasses.
Choose Iplanar, take the plane vs. the tube.
ICON Scientific, Inc
