Sixteen column solution for continuous separation
The AZURA Pilot SMB System A29503 is optimized for the separation of binary mixtures in gram to several hundred gram-scale. Its special emphasis is put on the continuous operation mode and high productivity. The system configuration consists of four Pump 2.1L and seven 16-port multiposition valves integrated into four AZURA Assistans ASM 2.1L. Our user friendly software PurityChrom® MCC and the required IT hardware are included too. Due to the high number of integratable columns, this system is the perfect solution for SMB separations of small molecules, whenever the separation process has to be optimzied very accurate as well as for challenging capture protein purification. A maximum pressure of 50 bar, 16 columns and a flowrate of up to 100 ml/min allows you to do a separation on columns up to 30 mm ID.
Choose your operation mode!
With our SMB-Systems you can easily switch between different operation modes:
Classical SMB Chromatography
The standard configuration is designed to run classical SMB separations. You can easily switch between different zone configurations. To switch from a classical 2:2:2:2 to a 1:3:3:1 configuration you just need to click one button in our software PurityChrom MCC. Other configurations can be chosen too.
Capture SMB
The flexible design of the SMB system allows you to run continuous FPLC purification after minor changes to the system. Use AZURA Lab SMB as your step to the future of biopurification and run your downstream process with the highest productivity and lowest costs. Parallel Batch Chromatography Just add detectors to the the System and run batch runs parallel or use the system for single batch runs. You could use an eight column setup to run four separations parallel for example.* The most flexible SMB System in the world Use a wide range of different upgrade options or just add a detector to build up a SMB chromatography system suits perfectly to your needs. Do you want to change the wetted parts? Contact us to get more information!
Available Upgrade-Kits
With our preconfigured Upgrade-Kits you can upgrade your SMB chromatography system very easily and build up the system you need.
| Upgrade-Kit | Art. No | |
|---|---|---|
| Flowmeter | With the CORI-Flow M14 you can monitor you SMB process and react instantly on every influence to the separation process (Single device or set of four flowmeter for full system monitoring). | A29802 (single) A29803 (set of four) |
| Heating | Add an oven to your SMB and take full control over the column temperature. Can be used for eight KNAUER columns up to 250 x 50 mm. | A29900 |
Technical Data
AZURA SMB systems
| Max. flow rate | 100 ml/min |
|---|---|
| Recommended flow rate | 2-40 ml/min |
| Maximum delivery pressure [psi] | 730 psi |
| Maximum delivery pressure [bar] | 50 bar |
| Maximum delivery pressure [MPa] | 5 MPa |
| Column configuration | 4:4:4:4 |
| Operating modes | classical SMB, MCCP*, batch* |
| Supported software packages | PurityChrom® MCC |
ICON Scientific, Inc
